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Dear Colleague,

The cost to discover and develop a drug is increasing dramatically in both Europe and the US, and the number of new drug products that are given approval is on the decline. Drug manufacturers are desperately searching for ways to increase the efficiency of the drug discovery process while decreasing the costs and time it takes for approvals.

Biomarkers are increasingly being used to answer specific questions that provide critical "go-no-go" decision/support data for compounds as they move down the pipeline and soak up more and more R&D dollars. It`s not very surprising that biomarkers are being used to measure clinical responses to a drug, to quantify drug-target interactions, to demonstrate the relevance of a molecule to the pathophysiology of a particular disease, and as safety indicators that can identify subjects who might react adversely to a drug. Biomarkers have become extraordinarily important at every stage of development of a compound and subsequent post-approval lifecycle management.

GTCBio’s 2^nd Annual Biomarker Discovery Europe Conference, to be held this October 1-2, 2009 in Lisbon, Portugal, will provide a focused look at the applications of biomarkers throughout the drug discovery process. The conference will provide tools on how to incorporate biomarkers into your discovery programs and translational research for better results. We will discuss new strategies & technologies for biomarker discovery, as well as highlight biomarkers that are currently in clinical trials.

The conference features the following sessions:

Biomarker Discovery Europe 2009
I: New Developments and Technologies in Biomarker Discovery
II: Overcoming the Discovery to Validation Bottleneck
III: Approach to Formulation & Drug Delivery of Biomarkers
IV: Biomarkers in Oncology
V: Biomarkers in Translational Research
VI: Biomarkers in Clinical Development

We look forward to seeing you at the conference!


Best regards,

- 2009 Conference Advisory Committee

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