2nd Annual Future of Biobased Chemicals - Inception to Marketplace
The 3rd Biobased Chemicals Commercialization & Partnering Conference is Scheduled for 2012!
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Day 1 Day 2
 
Day 1 - Thursday, July 7, 2011
   
7:00 Registration & Continental Breakfast
   
7:55 Welcome & Opening Remarks
  David T. Quinby, Partner, Stoel Rives LLP
   
Session I
Creating Market Pull for Biobased Chemicals
Moderator: David T. Quinby, Stoel Rives LLP
   
8:10 Sustainable Drop-Ins: Product Pull through Competitive Economics and Differentiated Performance
  Steve del Cardayre, Vice President, Research & Development, LS9
   
  LS9 has developed a platform technology for the sustainable production of a diversity of fuels and chemicals. The heart of the technology lies in the selectivity and efficiency of our engineered microbial catalysts and the simple cost-effective processes they enable. LS9 has initially focused on the production of existing products for which established and growing markets exist. The LS9 platform enables market pull through competitive pricing, feedstock and supplier alternatives, and sustainability. The LS9 technology in addition enables the tailoring of molecule structure and performance at a level not previously possible, which allows for the production of differentiated products with enhanced performance and economic benefits.
   
8:35 Priming the Pump – Preparing the Supply Chain for Bio-BDO
  Damien Perriman, Vice President, Business Development, Genomatica
   
  A presentation on the application validation steps for building market acceptance and excitement for a biobased product. The presentation will cover Genomatica’s scale up results for Bio-BDO and discuss details of the recently announced collaboration with Tate & Lyle for demonstration scale production. Balancing the demands for sample material from numerous prospects will be contrasted with production volumes during scale up. Issues like material quality and pricing will also be discussed, particularly on the light of 1st to market opportunities.
   
9:00 Commercialization of Javelin Technology: From Lab to Retail Shelf
  Cora Leibig, Vice President, Research and Development, Segetis
   
  JavelinTM Technology from Segetis is a new-to-the-world biobased chemical platform. Segetis is actively commercializing solvents and plasticizers based on the technology in applications ranging from household cleaners to paints to construction vinyl. Commercialization has required success on many fronts including product development, regulatory approval, process development and scale-up, and supply-chain development.

Benefits:
- Description of how to develop and position new-to-the-world products on market
- Description of markets most receptive to “green” or “bio-based” value prop
- Scale-up strategies which minimize capital expenditure
- Partnership development
   
9:25 USDA BioPreferredSM Program “Double Your Market Advantage”
  Rudy Pruszko, Business and Industry Field Specialist, Center for Industrial Research and Service (CIRAS)
   
  The presentation will provide a brief background of the BioPreferredSM Program and the new USDA Labeling Program. It will answer the question “What is the BioPreferred Program” and discuss the Federal Procurement Preference Program, labeling initiative and future issues associated with the programs. The benefits of attending the presentation is gaining knowledge about the various programs, how to improve the marketing of your products, how to obtain a USDA Certified Label, and what the future holds for the program.
   
9:50 Networking & Refreshment Break
   
Session II
Industry Update: New Technologies and Platforms Influencing Biobased Chemical Production
Moderator: David T. Quinby, Stoel Rives LLP
   
10:20 Transforming Industrial Biotechnology
  Johan van Walsem, Vice President of Strategy and Commercial Development, Metabolix
   
  Metabolix is a bioscience company and pioneer in the development of biobased plastics and chemicals using bio-renewable feedstocks. The company develops innovative solutions by combining its expertise in industrial biotechnology (multi-gene systems, microbial engineering and plant biotechnology) with engineering excellence (systems integration and pilot manufacturing) to address global markets. Metabolix applies its expertise in Polyhydroxyalkanoate (PHA) chemistry to two primary pathways: fermentation and industrial crop development. The first commercial platform from our fermentation pathway is Mirel Bioplastics. Mirel provides product and packaging options that can respond to the strong societal and market drivers for transitioning from petroleum to biobased solutions.

During this presentation, we will discuss our fermentation based portfolio of products including Mirel, our bioplastic commercialized through a Joint Venture with Archer Daniels Midland. Metabolix has also created a fermentation pathway for C4 chemical development. Our years of experience in fermentation leads to an accelerated development pathway to commercialization for this new product portfolio. The company is in the pre-commerical stages of developing specialty C4 (pyrrolidone derivatives) chemicals. These products offer very robust economics based on our advantaged process. This presentation will cover the scale-up activities for the first C4 chemicals as well as the industrial chemicals to follow (BDO and acrylates). These second generation chemicals have an addressable market over $10

ion and the company’s transformational technologies and scalability will result in lower costs for these products. Our presentation will also cover the global nature of these developing technologies and the potential commercial markets they could positively impact.
   
10:45 Moving Bio-Based Resins through the Value Chain for Green Buildings
  Joe Fox, Director, Emerging & External Technologies, Ashland
   
  This presentation will describe the value chain for commercializing a family of new, bio-based building products using resin intermediates made with biorenewable raw materials. The resin intermediates are unsaturated polyester resins that have been made using soybean oil, corn-derived ethanol and/or other chemical building blocks obtained from biomass. The building products include countertops, tubs and showers, and restaurant furniture. Efforts to increase awareness of these products at GreenBuild and via the new website www.compositebuild.com will be described.

Benefits:
• Learn about the value chain for green building materials and where Ashland participates in this chain.
• Learn about the chemistry of Ashland’s bio-based EnvirezTM resins.
• See examples of commercial building products made with bio-based composite resins and adhesives.
• Learn about the recently-launched website: www.compositebuild.com
   
11:10 Opportunities and Challenges for a New Foundation for Bio-based Chemicals
  Peter Keeling, Director of Innovation & Industry Collaboration, Center for Biorenewable Chemicals (CBiRC)
   
  CBiRC is developing the tools, components and materials needed to transform carbohydrate feedstocks into bio-based chemicals. Core knowhow and technologies include bioengineering of fatty acid and polyketide biochemistry in microorganisms, as well as an innovative and complimentary portfolio of developments in chemical catalysis. By combining biocatalysis and chemical catalysis CBiRC creates new knowhow and powerful technologies that have the potential to nurture a sustainable bio-based chemical industry. CBiRC believes the existing petrochemical supply chain can be transformed with key foundational intermediates that deliver an array of drop-in chemistry or similar functionality to existing fossil-carbon-based chemicals. Here we will describe our progress towards creating a new foundation for bio-based chemicals.
   
11:35 Biofuels & Biochemicals Production in a Biorefinery
  Manoj Kumar, Director Science & Technology, Global New Business Development, DSM Bio-Based Products and Services
   
  DSM brings a sustainable operational history and an industry leading skill-set in the field of Industrial Biotechnology to the challenge of Biorefining. We are leveraging the longstanding competencies and knowledge derived from the biotechnology, chemistry, and operational components of DSM.

In this presentation, we will describe our work and success achieved for sustainable biorefining for making biochemicals and advanced biofuels based upon full integration of all operational and technology elements that has been developed concurrently within powerful industry partnerships.

We will provide data to illustrate that today’s business model for the supply of bioproducts software into the Bioethanol/biofuels/Bio-based chemicals and materials market sector will not be sustainable for the future, whereby such products will need to be manufactured within the boundaries of the Biorefinery itself. Biomass saccharifying cellulase enzymes cocktails manufacturing will have to be fully integrated into such a Biorefinery or it could be connected as a “on site” or “bolt-on” facility. Additional key elements of integration will include, amongst others, co-development and deployment of suitable fermentation organisms that are capable to metabolize mixed sugars simultaneously along with effective pre-treatment technologies that generate hydrolysates and or hydrolysable substrates.

We will illustrate that the above focus on integration and the ability to impact all relevant process technologies will create, through compelling economics, a strong sustainable advantage for Biorefinery practitioners on a global basis.

Benefits:
1. Better understanding of sustainability requirement of our world to deliver products and services for both current and future needs.
2. With Petroleum at $100/barrel and peak output has reached, biomass and biorefineries are the only option left for producing renewable liquid fuel for transportation and sugars for making chemicals.
   
12:00 Renewable Products for Industrial Applications
  Laura Martin, Commercial Development Manager, POET
  The specialty chemical industry, which is primarily based on petroleum based products, generates $860 billion in annual economic activity worldwide. There are many renewable products manufactured from emerging biorefineries that can replace those products. New ethanol co-products can help ethanol plants become true biorefineries, unlocking the additional potential of each kernel of corn. Cellulosic biorefineries can also provide new opportunities since diverse feedstock leads to new products. This presentation will highlight renewable specialty chemicals produced from POET biorefineries for food and industrial applications.
   
12:25 Lunch On Your Own
   
Session II
Industry Update: New Technologies and Platforms Influencing Biobased Chemical Production (Cont.)
Moderator: David T. Quinby, Stoel Rives LLP
   
2:00 Systems Biology and Novel Culturing System for Bio-Based Chemicals from Cyanobacteria
  F. Blaine Metting, Biological & Environmental Sciences Product Line Manger, Battelle Memorial Institute, Pacific Northwest National Laboratory
   
  Systems biology research at PNNL focuses on nitrogen-fixing cyanobacteria (blue-green algae) in an effort to improve existing understanding of bio-fuels and bio-products production by a using a metabolic modeling approach for simulating the fundamental metabolic and regulatory controls in these organisms. The research addresses the potential for production of high value compounds as well as bio-hydrogen and other fuels based on metabolic engineering. The research has also resulted in novel, proprietary dual culture systems for cost-effective production of fuels and products from industrial waste streams and sunlight. Variations of the co-culture approach will be described for selected fuels and products.
   
2:25 Chemicals and Biofuels from Underutilized Biomass Feedstocks: Biorefinery Strategies for the West
  William J. Orts, Research Leader, Bioproduct Chemistry & Engineering, USDA - ARS - WRRC
   
2:50 Farnesene: Applications for a Bio-Renewable Feedstock
  Adam Safir, Director, Polymer Science, Amyris Biotechnologies
   
3:15 Overcoming Feedstock Challenges for Biochemical Production
  Gregory Boholmann, Director of Business Development, Genencor/Danisco
   
3:40 Networking & Refreshment Break
   
4:10 Production of Biofuels/Biochemicals from Non-Food Based Biomass by the RITE bioprocess
  Hideaki Yukawa, Director, Molecular Microbiology and Biotechnology Group, RITE-Research Institute of Innovative Technology for the earth
   
  In order to combat global warming and find alternatives to the increasingly scarce fossil fuel resources, the world’s attention is focused on renewable biomass as the most sustainable resource for future biofuel and commodity chemicals. At RITE, we developed the "RITE bioprocess" to utilize “soft biomass” to produce biofuels and chemicals. This talk highlights our experiences in developing our bioprocess.

 - The U.S. set a valuable example for the rest of the world to emulate; developing new technologies based on the biorefinery concept must be a strongly promoted national policy. It resulted in a significant increase in U.S. production of bio-ethanol, the representative product of the biorefinery concept, over a short time span.
 - Most current biofuel production processes utilize food crops, and bio-ethanol production was inevitably blamed for recent high food prices. There is, therefore, a persistent need to shift to "soft-biomass", obtained from non-food crops as well as inedible parts of food crops, as the demand for the biofuels will only increase. Our bioprocess adapts well to disparate substrates.
 - The RITE bioprocess utilizes Corynebacterium glutamicum, which is already widely used in industrial production of amino acids. The bioprocess is, however, based on a new concept that fundamentally resolves many of the technological problems of conventional bioprocesses. It is very versatile in the range of products possible.
 - To demonstrate this versatility, ethanologenic C. glutamicum strains densely packed in a reactor under growth-arrested conditions enabled high volumetric productivity of various chemicals. Cells were able to utilize mixed sugar substrates derived from lignocellulosic biomass.
   
Session III
The Financial Future of Biobased Chemicals: Securing Funding and Strategic Partnerships
Moderator: David T. Quinby, Stoel Rives LLP
   
4:35 The Role of Intellectual Property in Securing Funding and Strategic Partnerships
  Gladys Monroy, Senior Partner, Morrison & Foerster
   
5:00 Leveraging the Value Chain of Partnerships for Bio-based Chemicals
  Dan Verser, Executive VP of Research & Development and Founder, ZeaChem Inc.
   
  ZeaChem is a producer of economical and sustainable advanced biofuels and bio-based chemicals. Using a variety of feedstock resources, ZeaChem is developing multiple product platforms as alternatives to petroleum-based products.

Successfully bringing bio-based chemicals to market requires many partners along the value chain. The first key to success is feedstock supply. ZeaChem is working with GreenWood Resources (GWR), the nation’s leader in hybrid poplar tree management, as the primary feedstock provider for ZeaChem’s demonstration scale biorefinery and first commercial production facility. In addition, local agricultural residues will supply supplemental feedstock.

Second, ZeaChem is using known processes and equipment from well respected industry vendors including KMPS and Sulzer. The process components are integrated in a novel way, significantly reducing scale-up and financing risk of biorefinery facilities.

Third, off-take partners will bring ZeaChem’s products to market. ZeaChem has off-take agreements in place from its demonstration scale facility and is developing agreements for its first commercial biorefinery.

Forth, financial, product development and market pull through partners play a vital role in commercializing bio-based chemicals. ZeaChem is developing relationships in all of these areas to accelerate commercialization of its bio-based chemical platforms.

Benefits:
1. Explore the value chain of partnerships needed to bring bio-based chemicals to market.
2. Understand the unique role for each type of partner.
3. Discuss how the integration of these partners will successfully commercialize bio-based chemicals.
   
5:30 Networking Reception
   
  Poster Abstract
  Richa Tungal, Department of Chemical and Biological Engineering, South Dakota School of Mines & Technology
   
Day 1 Day 2
   
Day 2 - Friday, July 8, 2011
   
7:30 Continental Breakfast
   
Session III
The Financial Future of Biobased Chemicals: Securing Funding and Strategic Partnerships (Cont.)
   
8:25

 Panel Discussion
  Panel Moderator: David T. Quinby, Partner, Stoel Rives LLP
  Panelists:
  Doug Cameron,Founder and Managing Director, Alberti Advisors, LLC
  Cora Leibig, Vice President, Research and Development,Segetis
  Damien Perriman, Vice President, Business Development, Genomatica
  Ajay Kshatriya, Head of Commercial, Bio Architecture Lab Inc.
   
Session IV
Biobased Chemical Challenges – Lab to Commercial Scale Up
Moderator: Barbara Balos Bowker
   
9:10 Launching the Bio-PDO™ Platform – The Sorona® Story
  Ray W. Miller, Global Business Development Manager, BioMaterials and Specialties, DuPont Applied BioSciences
   
  DuPont is rapidly evolving from a 200+ year old chemicals and materials company to an industrial biotechnology powerhouse. Ray will briefly explain the driving forces behind this transformation and outline DuPont’s approach to the development and commercialization of sustainable materials and energy offerings. He will focus heavily on the development and commercial introduction of the Sorona® polymer business, and the subsequent development of bio-sourced 1,3 propanediol (Bio-PDO?) as well as progress being made to broaden the offerings of value-added specialties based on this initial platform molecule. The presentation will explain the necessity of understanding the markets and what they require to be able to create market pull for new materials vs. incumbents from petroleum sources. Ray will conclude with some suggestions on the role of governments in helping businesses achieve a fundamental shift away from petroleum dependency in our materials and fuels industries.

Members of the audience will learn:
- motivations for bio-based fuels and chemicals
- how to establish a market for materials that are not a “drop-in”
- how to persevere when the going gets tough
- how governmental policy can influence success
   
9:35 Developing the Biorefineries of the Future
  Mark Warner, Senior Vice President, Process Industries, Harris Group (Seattle)
   
  There are various technical pathways that can be used for converting forest residuals and other biomass into bio-based chemicals and liquid transportation fuels. This presentation will review the technical and economic advantages of the most promising technologies, along with the pathways for scaling up to commercial production. This session will provide a unique perspective on scale-up, performance guarantees and financing considerations.

• Understanding of commercially available technologies of making bio-based chemicals.
• Unique perspective of mix of technical and economic perspectives.
• Perspective of industry leaders currently involved in commercialization of multiple biomass conversion technologies.
• Experience with biomass, algae, sugars, municipal solid waste and most commonly available biomass sources.
   
10:00 Networking & Refreshment Break
   
10:40 Myriant’s Path to Succinic Acid Commercialization
  Samuel G. McConnell, Senior Vice President, Corporate Development, Myriant Technologies, Inc.
   
  In the past year Myriant Technologies has announced two deals that have accelerated the company’s commercial bio-based Succinic Acid (SAC) program. PTT, with an investment of $60 million, provides capital to the world’s first bio based SAC plant under construction by Myriant in Lake Providence, LA. In addition, Davy and Myriant, through an exclusive partnership, will develop and offer bio-based Butanediol (BDO). Davy is the world’s premier BDO licensor and has over 1 billion lbs of production capacity installed globally. Davy will now offer Myriant’s SAC as a feedstock for existing and future BDO plants in addition to developing an integrated sugar to BDO process by integrating the Myriant SAC process with the Davy BDO process.

Myriant’s SAC plant in Lake Provide is currently under construction with the support of PTT and a $50 million grant by the Department of Energy (DOE). The plant is slated to be completed the second half of 2012, and will have a production capacity of 30 million lbs/year.
In addition to the Davy market channel, Myriant has also concluded several contracts for the purchase of SAC from customers in the plasticizer, urethane and solvent markets.

Myriant will present the company’s critical next steps in the commercialization of bio SAC and the company’s over-all commercial SAC strategy. In addition, the company will describe opportunities, pit falls and lessons learned on the road to commercializing SAC.
   
Session IV
Advanced Biofuels: Developments, Sustainability and Commercialization
Moderator: Barbara Balos Bowker
   
11:05 Designer Triglyceride Oils and Renewable Chemicals
  Walter Rakitsky, VP Strategy & Emerging Businesses, Solazyme
   
  Solazyme has developed a unique and proprietary industry-leading microbial chemicals platform which exploits designer triglyceride oils as the basis for the next generation of high performance bio-based fluids and green chemicals. Solazyme’s core technology utilizes microalgae to transform carbohydrate feedstocks into fatty acids in the triglyceride form. These triglyceride oils can then be converted through biological or chemical routes to numerous value-added chemicals, such as surfactants, lubricants and polymers in existing industry infrastructure. Properties of the designer oils are manipulated to increase their value over existing renewable oils by optimizing chain length distribution and levels of saturation. Solazyme’s industrial fermentation manufacturing platform allows production of thousands of tons of designer oils from multiple carbohydrate feedstocks and thus can be deployed worldwide. In this presentation, we will discuss how and why Solazyme’s renewable chemicals platform expands the possibilities for further replacements of petroleum derived oils with renewable, sustainable alternatives.
   
11:30 Replacing Petrochemical Aromatics with BioFormPXTM and Other Bio-Based Alternatives
  Kieran Furlong, Commercial Manager, Virent Energy Systems
   
  The interest in and demand for alternative sources of aromatic chemical intermediates have significantly increased in recent years for a number of reasons. Consumers, major retailers and non-governmental organizations have all called for more sustainable packaging and materials. Consumer brand companies see marketing potential in “greener” packaging. Manufacturers have suffered increased volatility and rising costs due to crude oil pricing. Many of the polymers widely used in consumer packaging and products are produced from aromatic intermediates (polyester from paraxylene; polystyrene from benzene; etc). All of this has directed focus towards bio-based alternatives. Virent has successfully demonstrated the production of biobased paraxylene, which – when combined with existing bio-MEG – enables a fully bio-based, renewable, recyclable PET/polyester polymer. This presentation will describe Virent’s novel BioFormPX™ including the production process, and how other aromatics chemicals and fuels are produced using the same technology.

Members of the audience will learn
- how this technology allows the production of the first 100% bio-based PET bottle or polyester fiber
- how similar the bio-based paraxylene is to the conventional petro-based material
- how the production of bio-based chemicals interacts with the production of fuel in a bio-refinery
- the economic parameters for the commercialization of bio-based PX
   
12:00 

 Lunch provided by GTC
   
   
2:30

Conference Concludes
   
Day 1 Day 2
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