Philipp Ottis obtained his undergraduate degree in Biology from the University of Cologne, Germany, involving research in analytical natural compounds chemistry. Staying in Cologne, for his Master’s degree, Philipp focused on biochemical studies and research on post-translational protein modification. For his doctoral work, he joined the lab of Carsten Korth at the University of Dusseldorf, Germany, where Philipp studied aberrant protein accumulation associated with proteostasis impairment in brain aging and disease. Amongst other things, his work led to the identification of a previously unknown interaction of two major Schizophrenia risk-factor proteins and the Ziskind-Somerfeld Award of the Society of Biological Psychiatry.
Switching general research fields, yet staying with protein quality control, Philipp currently is a postdoctoral research associate in the group of Craig Crews at Yale University employing the Proteolysis Targeting Chimera (PROTAC) technology to target previously “undruggable” proteins and to study various downstream effects induced by spatio-temporally controlled ubiquitylation.